https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:25338 s = 0.398, P = 0.015) and (r_s = 0.455, P = 0.005) respectively), with 1.7% greater absolute weight loss at week 10 corresponding to each one unit reduction in the asthma-related quality of life score at baseline. Furthermore, a lower baseline forced expiratory volume in 1 s/forced vital capacity correlated with greater weight loss (r_s = 0.398, P = 0.015). Male sex was associated with a 3.6 kg greater weight loss (P = 0.087). Reducing emotional eating during the programme was associated with greater weight loss in women (r_s = 0.576, P = 0.010). Conclusions This study demonstrates that individuals with more severe asthma at baseline are more successful in achieving weight loss, which could be a consequence of greater motivation and could be used as a motivational tool within the clinical setting. Gender tailoring of weight loss programmes may be useful to enhance weight loss success. Future studies are urgently needed to establish predictors of long-term weight loss maintenance in those with asthma. See Editorial, page 179 This study is the first to demonstrate that more severe asthma at baseline, male sex, and improvements in eating behaviours during weight loss are associated with greater weight loss success in overweight and obese adults with asthma. Our findings may inform the development of asthma-specific weight management guidelines.]]> Wed 11 Apr 2018 16:17:48 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12899 Wed 11 Apr 2018 15:23:55 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:24115 Wed 11 Apr 2018 11:19:58 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:10954 = 40) increased from 3% in 1987 to 16% in 2007. Median AHI progressively increased from 1992-1995 to 2004-2007 (from 65 events/h to 143 events/h, P < 0001), indicating increasing disease severity. Over the same period, for every unit increase in BMI, AHI increased by 5 5 events/h for men and by 2 8 events/h for women. About 80% of the observed variance in AHI over this period was attributable to variance in BMI. Conclusion: There is a continuing trend towards increasing body weight and BMI in people undergoing diagnostic sleep studies. Our data do not support the hypothesis that increased accessibility to diagnostic services and increased awareness of sleep disorders are resulting in a decline in disease severity. These findings are consistent with the premise that worsening severity in sleep-disordered breathing is primarily attributable to increasing obesity.]]> Sat 24 Mar 2018 08:14:14 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:10921 Sat 24 Mar 2018 08:10:56 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18137 Sat 24 Mar 2018 08:04:44 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18132 Sat 24 Mar 2018 08:04:28 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:17502 , FVC and FEF25-75% from 11654 white males and 11113 white females, aged 3-94 years, routinely tested in the pulmonary function laboratories of four tertiary hospitals. FEF75% was available in 8254 males and 7407 females. Predicted values and lower limits of normal, defined as the fifth percentile, were calculated for FEV1, FVC, FEV1/FVC ratio, FEF25-75% and FEF75% using prediction equations from the Global Lung Function Initiative. There was very little discordance in classifying test results. FEF25-75% and FEF75% were below the normal range in only 2.75% and 1.29% of cases, respectively, whereas FEV1, FVC and FEV1/FVC ratio were within normal limits. Airways obstruction went undetected by FEF25-75% in 2.9% of cases and by FEF75% in 12.3% of cases. Maximum mid-expiratory flow and flow towards the end of the forced expiratory manoeuvre do not contribute usefully to clinical decision making over and above information from FEV1, FVC and FEV1/FVC ratio.]]> Sat 24 Mar 2018 08:04:05 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:16918 1)/(forced) vital capacity ((F)VC) ratio below the fifth percentile and graded the severity of pulmonary function impairment using z-scores for FEV₁, which signify how many standard deviations a result is from the mean predicted value. Using the lower limit of normal for FEV₁/(F)VC and z-scores for FEV₁ of -2, -2.5, -3 and -4 to delineate severity grades of airflow limitation leads to close agreement with ATS/ERS severity classifications and removes age, sex and height related bias. The new classification system is simple, easily memorised and clinically valid. It retains previously established associations with clinical outcomes and avoids biases due to the use of per cent predicted FEV₁. Combined with the Global Lung Function prediction equations it provides a worldwide diagnostic standard, free of bias due to age, height, sex and ethnic group.]]> Sat 24 Mar 2018 08:00:32 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:21333 Sat 24 Mar 2018 07:52:48 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18362 Sat 24 Mar 2018 07:52:40 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18365 Sat 24 Mar 2018 07:52:40 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18364 LLN and FVC20% underdiagnosis of airway obstruction up to the age of 55 years and to 16-23% overdiagnosis in older subjects. GLI 2012 equations increase the prevalence of a "restrictive spirometric pattern" compared to ECSC but decrease it compared to NHANES.]]> Sat 24 Mar 2018 07:52:39 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18366 Sat 24 Mar 2018 07:52:38 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20658 Sat 24 Mar 2018 07:49:55 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:28324 Sat 24 Mar 2018 07:25:14 AEDT ]]>